{"id":3215,"date":"2025-10-06T05:52:40","date_gmt":"2025-10-06T05:52:40","guid":{"rendered":"https:\/\/genoks.com.tr\/docs\/array-cgh-en\/"},"modified":"2026-05-02T05:05:29","modified_gmt":"2026-05-02T05:05:29","password":"","slug":"array-cgh-en","status":"publish","type":"docs","link":"https:\/\/genoks.com.tr\/en\/docs\/array-cgh-en\/","title":{"rendered":"Array-CGH"},"content":{"rendered":"<p><!--genoks-intro-en:start--><\/p>\n<p><strong>Array-CGH (Comparative Genomic Hybridization)<\/strong> is a microarray-based cytogenetic test detecting copy-number variants (CNVs) \u2014 gains and losses of DNA \u2014 across the entire genome at resolutions of 50-100 kb (much higher than karyotype&#8217;s ~5-10 Mb). Recommended first-tier test for unexplained developmental delay, intellectual disability, autism, and multiple congenital anomalies. Does not detect balanced rearrangements, point mutations, or low-level mosaicism. Reporting: 5-10 days.<\/p>\n<p><!--genoks-intro-en:end--><\/p>\n<p style=\"text-align: justify\"><strong>Array CGH Nedir ?<\/strong><br \/>\nArray CGH (Comparative Genomic Hybridization), genetik materyalin (DNA) kopya say\u0131s\u0131ndaki de\u011fi\u015fiklikleri tespit etmek i\u00e7in kullan\u0131lan bir molek\u00fcler sitogenetik teknolojisidir. Bu teknoloji, bir\u00e7ok genetik hastal\u0131\u011f\u0131n tan\u0131s\u0131nda ve ara\u015ft\u0131rmalar\u0131nda kullan\u0131lmaktad\u0131r.<\/p>\n<p style=\"text-align: justify\">Array CGH, bir mikroarray platformu \u00fczerine yerle\u015ftirilmi\u015f DNA prob dizilerinin kullan\u0131lmas\u0131yla \u00e7al\u0131\u015f\u0131r. Normal bir \u00f6rnekle hasta bir \u00f6rne\u011fin DNA&#8217;s\u0131 kar\u015f\u0131la\u015ft\u0131r\u0131l\u0131r ve bu sayede kopya say\u0131s\u0131ndaki de\u011fi\u015fiklikler tespit edilir. Normal bir \u00f6rnekteki DNA prob dizileri ile hastal\u0131kl\u0131 \u00f6rnekteki DNA prob dizileri kar\u015f\u0131la\u015ft\u0131r\u0131l\u0131r ve kopya say\u0131s\u0131nda art\u0131\u015f veya azalma oldu\u011fu tespit edilirse bu bir genetik de\u011fi\u015fiklik veya mutasyona i\u015faret eder.<\/p>\n<p style=\"text-align: justify\">Array CGH, kanser gibi bir\u00e7ok hastal\u0131\u011f\u0131n tan\u0131s\u0131nda ve tedavisinde kullan\u0131lmaktad\u0131r. \u00d6rne\u011fin, kanser h\u00fccrelerinde genetik de\u011fi\u015fiklikler s\u0131k\u00e7a g\u00f6r\u00fclmektedir ve bu de\u011fi\u015fiklikler, kanser h\u00fccrelerinin normal h\u00fccrelerden farkl\u0131la\u015fmas\u0131na neden olur. Array CGH, kanser h\u00fccrelerindeki bu genetik de\u011fi\u015fiklikleri tespit ederek, kanserin tan\u0131s\u0131nda ve tedavisinde \u00f6nemli bir ara\u00e7 olabilir.<\/p>\n<p style=\"text-align: justify\">Array CGH ayr\u0131ca, kal\u0131tsal hastal\u0131klar\u0131n tan\u0131s\u0131nda da kullan\u0131l\u0131r. Kal\u0131tsal hastal\u0131klar\u0131n baz\u0131lar\u0131, genlerdeki kopya say\u0131s\u0131 de\u011fi\u015fikliklerinden kaynaklan\u0131r ve Array CGH, bu de\u011fi\u015fiklikleri tespit etmeye yard\u0131mc\u0131 olabilir.<\/p>\n<p style=\"text-align: justify\">Array CGH&#8217;nin di\u011fer bir avantaj\u0131, bir\u00e7ok geni ayn\u0131 anda analiz edebilmesidir. B\u00f6ylece, bir\u00e7ok genetik de\u011fi\u015fikli\u011fin ayn\u0131 anda tespit edilmesi m\u00fcmk\u00fcn olur. Bununla birlikte, bu teknolojinin baz\u0131 s\u0131n\u0131rlamalar\u0131 da vard\u0131r. \u00d6rne\u011fin, bu teknoloji yaln\u0131zca kopya say\u0131s\u0131ndaki de\u011fi\u015fiklikleri tespit edebilir ve gen mutasyonlar\u0131n\u0131 veya epigenetik de\u011fi\u015fiklikleri tespit edemez.<\/p>\n<p>&nbsp;<\/p>\n<hr \/>\n<table>\n<tbody>\n<tr>\n<td><strong>Y\u00f6ntem :<\/strong><\/td>\n<td>Array-CGH<\/td>\n<\/tr>\n<tr>\n<td><strong>Raporlama S\u00fcresi :<\/strong><\/td>\n<td>4-6 Hafta<\/td>\n<\/tr>\n<tr>\n<td><strong><strong>Prenatal\/ Postnatal:<\/strong><\/strong><\/td>\n<td>Postnatal<\/td>\n<\/tr>\n<tr>\n<td><strong>Gerekli Numune<\/strong>:<\/td>\n<td>EDTA&#8217;l\u0131 Kan (2-4 ml)<\/td>\n<\/tr>\n<tr>\n<td><strong><strong>Algoritma\/A\u00e7\u0131klama<\/strong><\/strong><\/td>\n<td>Analiz s\u0131ras\u0131nda detayl\u0131 klinik bilgi gereklidir.<\/td>\n<\/tr>\n<tr>\n<td><strong>Saklama \/ Ta\u015f\u0131ma S\u0131cakl\u0131\u011f\u0131:<\/strong><\/td>\n<td>+ 4C\u00b0\/ + 24C\u00b0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>T\u00fcm genetik testlerimiz <strong>&#8220;Hasta Onam Formu&#8221;<\/strong> ve <strong>&#8220;KVKK Formu&#8221;<\/strong>nun imzalanmas\u0131n\u0131n ard\u0131ndan \u00e7al\u0131\u015f\u0131lmaya ba\u015flan\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Array-CGH (Comparative Genomic Hybridization) is a microarray-based cytogenetic test detecting copy-number variants (CNVs) \u2014 gains and losses of DNA \u2014 across the entire genome at resolutions of 50-100 kb (much higher than karyotype&#8217;s ~5-10 Mb). Recommended first-tier test for unexplained<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"doc_category":[204],"doc_tag":[],"class_list":["post-3215","docs","type-docs","status-publish","hentry","doc_category-genoks-gdhm-genetic-tests"],"aioseo_notices":[],"year_month":"2026-05","word_count":429,"total_views":0,"reactions":{"happy":0,"normal":0,"sad":0},"author_info":{"name":"admin","author_nicename":"admin","author_url":"https:\/\/genoks.com.tr\/en\/author\/admin\/"},"doc_category_info":[{"term_name":"Genoks GDHM Genetic Tests","term_url":"https:\/\/genoks.com.tr\/en\/docs-category\/genoks-gdhm-genetic-tests\/"}],"doc_tag_info":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.5.2 - aioseo.com -->\n\t<meta name=\"description\" content=\"Array-CGH (Comparative Genomic Hybridization) is a microarray-based cytogenetic test detecting copy-number variants (CNVs) \u2014 gains and losses of DNA \u2014 across the entire genome at resolutions of 50-100 kb (much higher than karyotype&#039;s ~5-10 Mb). 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Recommended first-tier test for unexplained developmental delay, intellectual disability, autism, and multiple congenital anomalies. Does not detect balanced rearrangements, point","twitter:creator":"@Genoks_GHTM","twitter:image":"https:\/\/genoks.com.tr\/wp-content\/uploads\/2025\/06\/genoks.svg"},"aioseo_meta_data":{"post_id":"3215","title":null,"description":null,"keywords":null,"keyphrases":null,"primary_term":null,"canonical_url":null,"og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":null,"og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":false,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":null,"robots_max_videopreview":null,"robots_max_imagepreview":"large","priority":null,"frequency":null,"local_seo":null,"seo_analyzer_scan_date":"2026-05-02 05:14:30","breadcrumb_settings":null,"limit_modified_date":false,"reviewed_by":null,"open_ai":null,"ai":null,"created":"2026-05-01 14:34:32","updated":"2026-05-02 05:31:51"},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/genoks.com.tr\/en\/\" title=\"Home\">Home<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/genoks.com.tr\/en\/Genoks\/\" title=\"Dok\u00fcmanlar\">Dok\u00fcmanlar<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/genoks.com.tr\/en\/docs-category\/genoks-gdhm-genetic-tests\/\" title=\"Genoks GDHM Genetic Tests\">Genoks GDHM Genetic Tests<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\tArray-CGH\n<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/genoks.com.tr\/en\/"},{"label":"Dok\u00fcmanlar","link":"https:\/\/genoks.com.tr\/en\/Genoks\/"},{"label":"Genoks GDHM Genetic Tests","link":"https:\/\/genoks.com.tr\/en\/docs-category\/genoks-gdhm-genetic-tests\/"},{"label":"Array-CGH","link":"https:\/\/genoks.com.tr\/en\/docs\/array-cgh-en\/"}],"_links":{"self":[{"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/docs\/3215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/docs"}],"about":[{"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/types\/docs"}],"author":[{"embeddable":true,"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/comments?post=3215"}],"version-history":[{"count":1,"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/docs\/3215\/revisions"}],"predecessor-version":[{"id":3516,"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/docs\/3215\/revisions\/3516"}],"wp:attachment":[{"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/media?parent=3215"}],"wp:term":[{"taxonomy":"doc_category","embeddable":true,"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/doc_category?post=3215"},{"taxonomy":"doc_tag","embeddable":true,"href":"https:\/\/genoks.com.tr\/en\/wp-json\/wp\/v2\/doc_tag?post=3215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}