{"id":3278,"date":"2025-10-06T05:52:40","date_gmt":"2025-10-06T05:52:40","guid":{"rendered":"https:\/\/genoks.com.tr\/docs\/genoxhere-colon-23-en\/"},"modified":"2026-05-02T05:14:18","modified_gmt":"2026-05-02T05:14:18","password":"","slug":"genoxhere-colon-23-en","status":"publish","type":"docs","link":"https:\/\/genoks.com.tr\/en\/docs\/genoxhere-colon-23-en\/","title":{"rendered":"GenoXhere &#8211; Colon 23 Genes and Hereditary Colon Cancer"},"content":{"rendered":"<p><!--genoks-intro-en:start--><\/p>\n<p><strong>GenoXhere Colon \u2014 23 Genes and Hereditary Colon Cancer.<\/strong> Targeted germline panel for hereditary colorectal cancer evaluation: MLH1, MSH2, MSH6, PMS2, EPCAM (Lynch syndrome), APC, MUTYH (FAP\/MAP), STK11 (Peutz-Jeghers), SMAD4, BMPR1A (juvenile polyposis), POLE, POLD1 (polymerase proofreading-associated polyposis), among others. Indicated for early-onset CRC (\u226450y), Lynch tumor screening positive, polyposis phenotype, family history. Result-driven surveillance (colonoscopy from age 20-25 in Lynch carriers) is life-saving.<\/p>\n<p><!--genoks-intro-en:end--><\/p>\n<p style=\"text-align: justify\"><strong>Genetik Ge\u00e7i\u015fli Kolon Kanseri Nedir ?<\/strong><\/p>\n<p style=\"text-align: justify\">Genetik ge\u00e7i\u015fli kolon kanseri, kal\u0131tsal bir yatk\u0131nl\u0131\u011f\u0131 olan bireylerde daha s\u0131k g\u00f6r\u00fclen bir kolon kanseri t\u00fcr\u00fcd\u00fcr. Kal\u0131tsal kolon kanseri sendromlar\u0131 olarak da bilinirler. Bu hastal\u0131k, ailelerde belirgin bir \u015fekilde g\u00f6r\u00fcl\u00fcr ve genellikle birden fazla ki\u015fide g\u00f6r\u00fcl\u00fcr.<\/p>\n<p style=\"text-align: justify\">Genetik ge\u00e7i\u015fli kolon kanserinde, belirli bir genetik mutasyon nedeniyle kolon kanseri g\u00f6r\u00fclme riski artar. Bu mutasyonlar, normalde kolonun i\u00e7 duvar\u0131nda olu\u015fan poliplerin olu\u015fumunu te\u015fvik eder ve bu poliplerin baz\u0131lar\u0131 kansere d\u00f6n\u00fc\u015febilir.<\/p>\n<p style=\"text-align: justify\">Genetik ge\u00e7i\u015fli kolon kanseri tarama testleri ve d\u00fczenli kontrol ile erken te\u015fhis edilebilir ve tedavi edilebilir. Ayr\u0131ca, risk fakt\u00f6rlerini belirlemek i\u00e7in genetik testler de kullan\u0131labilir.<\/p>\n<div id=\"attachment_1566\" style=\"width: 2570px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-1566\" class=\"size-full wp-image-1566\" src=\"https:\/\/genoks.com.tr\/wp-content\/uploads\/2023\/04\/doctor-holographic-bowel-scan-projection-with-vital-signs-medical-records-scaled.jpg\" alt=\"Genetik Ge\u00e7i\u015fli Kolon Kanseri\" width=\"2560\" height=\"1707\" \/><p id=\"caption-attachment-1566\" class=\"wp-caption-text\">Genetik Ge\u00e7i\u015fli Kolon Kanseri<\/p><\/div>\n<table>\n<tbody>\n<tr>\n<td><strong>Gen :<\/strong><\/td>\n<td>APC | AXIN2 | BLM | BMPR1A | CDH1 | EPCAM | GALNT12 | GREM1 | MLH1 | MLH3 | MSH2 | MSH3 | MSH6 | MUTYH | NTHL1 | PMS2 | POLD1 | PTEN | RPS20 | SMAD4 | STK11 | TP53<\/td>\n<\/tr>\n<tr>\n<td><strong>Y\u00f6ntem :<\/strong><\/td>\n<td>NGS<\/td>\n<\/tr>\n<tr>\n<td><strong>Raporlama S\u00fcresi :<\/strong><\/td>\n<td>8 Hafta (+\/- 2 Hafta)<\/td>\n<\/tr>\n<tr>\n<td><strong><strong>Prenatal\/ Postnatal:<\/strong><\/strong><\/td>\n<td>Postnatal<\/td>\n<\/tr>\n<tr>\n<td><strong>Gerekli Numune<\/strong>:<\/td>\n<td>EDTA&#8217;l\u0131 Kan (2-4 ml)<\/td>\n<\/tr>\n<tr>\n<td><strong>Saklama \/ Ta\u015f\u0131ma S\u0131cakl\u0131\u011f\u0131:<\/strong><\/td>\n<td>+ 4C\u00b0\/ + 24C\u00b0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>T\u00fcm genetik testlerimiz <strong>&#8220;Hasta Onam Formu&#8221;<\/strong> ve <strong>&#8220;KVKK Formu&#8221;<\/strong>nun imzalanmas\u0131n\u0131n ard\u0131ndan \u00e7al\u0131\u015f\u0131lmaya ba\u015flan\u0131r.<\/p>\n<hr \/>\n<p><strong>Detayl\u0131 Bilgi Almak \u0130\u00e7in Bize Mesaj Atabilirsiniz.<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td>[contact-form-7 id=&#8221;710&#8243; title=&#8221;genetik ba\u015fvuru&#8221;]<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Genoks Genetik Hastal\u0131klar De\u011ferlendirme Merkezi T.C. Sa\u011fl\u0131k Bankanl\u0131\u011f\u0131nca denetlenen ve GHDM-SM\/06.15\/01 ruhsat numaras\u0131 ile hizmet veren sa\u011fl\u0131k kurulu\u015fudur. genoks.com.tr web sayfas\u0131nda bulunan bilgiler, genetik de\u011ferlendirme ve\/veya tan\u0131-te\u015fhis ama\u00e7l\u0131 kullan\u0131lmamal\u0131d\u0131r. T\u00fcm i\u00e7erikler bilgilendirme ama\u00e7l\u0131d\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>GenoXhere Colon \u2014 23 Genes and Hereditary Colon Cancer. Targeted germline panel for hereditary colorectal cancer evaluation: MLH1, MSH2, MSH6, PMS2, EPCAM (Lynch syndrome), APC, MUTYH (FAP\/MAP), STK11 (Peutz-Jeghers), SMAD4, BMPR1A (juvenile polyposis), POLE, POLD1 (polymerase proofreading-associated polyposis), among others.<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"doc_category":[204],"doc_tag":[105,106],"class_list":["post-3278","docs","type-docs","status-publish","hentry","doc_category-genoks-gdhm-genetic-tests","doc_tag-kalitsal","doc_tag-kanser"],"aioseo_notices":[],"year_month":"2026-05","word_count":355,"total_views":0,"reactions":{"happy":0,"normal":0,"sad":0},"author_info":{"name":"admin","author_nicename":"admin","author_url":"https:\/\/genoks.com.tr\/en\/author\/admin\/"},"doc_category_info":[{"term_name":"Genoks GDHM Genetic Tests","term_url":"https:\/\/genoks.com.tr\/en\/docs-category\/genoks-gdhm-genetic-tests\/"}],"doc_tag_info":[{"term_name":"Kal\u0131tsal","term_url":"https:\/\/genoks.com.tr\/docs-tag\/kalitsal\/"},{"term_name":"kanser","term_url":"https:\/\/genoks.com.tr\/docs-tag\/kanser\/"}],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.5.2 - aioseo.com -->\n\t<meta name=\"description\" content=\"GenoXhere Colon \u2014 23 Genes and Hereditary Colon Cancer. 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Targeted germline panel for hereditary colorectal cancer evaluation: MLH1, MSH2, MSH6, PMS2, EPCAM (Lynch syndrome), APC, MUTYH (FAP\/MAP), STK11 (Peutz-Jeghers), SMAD4, BMPR1A (juvenile polyposis), POLE, POLD1 (polymerase proofreading-associated polyposis), among others. Indicated for early-onset CRC (\u226450y), Lynch tumor screening positive, polyposis phenotype, family history. Result-driven surveillance","og:url":"https:\/\/genoks.com.tr\/en\/docs\/genoxhere-colon-23-en\/","og:image":"https:\/\/genoks.com.tr\/wp-content\/uploads\/2025\/06\/genoks.svg","og:image:secure_url":"https:\/\/genoks.com.tr\/wp-content\/uploads\/2025\/06\/genoks.svg","article:published_time":"2025-10-06T05:52:40+00:00","article:modified_time":"2026-05-02T05:14:18+00:00","article:publisher":"https:\/\/www.facebook.com\/GenoksGHTM","twitter:card":"summary_large_image","twitter:site":"@Genoks_GHTM","twitter:title":"GenoXhere \u2013 Colon 23 Genes and Hereditary Colon Cancer - Genoks Genetics | NIPT, Carrier Screening, Oncogenetics and WES Services","twitter:description":"GenoXhere Colon \u2014 23 Genes and Hereditary Colon Cancer. Targeted germline panel for hereditary colorectal cancer evaluation: MLH1, MSH2, MSH6, PMS2, EPCAM (Lynch syndrome), APC, MUTYH (FAP\/MAP), STK11 (Peutz-Jeghers), SMAD4, BMPR1A (juvenile polyposis), POLE, POLD1 (polymerase proofreading-associated polyposis), among others. Indicated for early-onset CRC (\u226450y), Lynch tumor screening positive, polyposis phenotype, family history. 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