{"id":3291,"date":"2025-10-06T05:52:40","date_gmt":"2025-10-06T05:52:40","guid":{"rendered":"https:\/\/genoks.com.tr\/docs\/genoxhere-brca-sr\/"},"modified":"2026-05-01T21:43:16","modified_gmt":"2026-05-01T21:43:16","password":"","slug":"genoxhere-brca-sr","status":"publish","type":"docs","link":"https:\/\/genoks.com.tr\/sr\/docs\/genoxhere-brca-sr\/","title":{"rendered":"\u0160ta je BRCA gen? \u0160ta obuhvata GenoXhere BRCA?"},"content":{"rendered":"

<\/p>\n

\u0160ta je BRCA gen? \u0160ta obuhvata GenoXhere BRCA?<\/strong><\/p>\n

BRCA1 i BRCA2 su tumor supresorski geni neophodni za popravku dvolan\u010danih prekida DNK putem homologne rekombinacije. Patogene germinativne varijante u bilo kojem od njih zna\u010dajno pove\u0107avaju do\u017eivotni rizik od raka dojke (~55-72% BRCA1, ~45-69% BRCA2), jajnika (~39-44% BRCA1, ~11-17% BRCA2), prostate, pankreasa i mu\u0161kog raka dojke. Panel GenoXhere BRCA sekvencira oba gena uklju\u010duju\u0107i velike preure\u0111aje (MLPA) i prijavljuje varijante prema kriterijumima ACMG\/AMP 2015.<\/p>\n

Ko treba da se testira:<\/strong> prema NCCN smernicama, li\u010dna\/porodi\u010dna istorija raka dojke u ranom dobu (\u226450 god), rak jajnika u bilo kom dobu, mu\u0161ki rak dojke, triple-negativni rak dojke \u226460 god, jevrejsko a\u0161kenaski porijeklo, metastatski rak prostate ili pankreasa. Klini\u010dka obrada nosilaca obuhvata godi\u0161nji MR dojke od 25 godina, mamografiju od 30, salpingo-ooforektomiju za smanjenje rizika do 35-40 (BRCA1) ili 40-45 (BRCA2) godina, i terapiju PARP inhibitorima kod odabranih karcinoma.<\/p>\n

<\/p>\n

BRCA Geni Nedir?<\/strong><\/p>\n

BRCA, meme kanseri ve yumurtal\u0131k kanseri gibi kanser t\u00fcrlerine yatk\u0131nl\u0131k olu\u015fturan genlerin ad\u0131d\u0131r. BRCA1 ve BRCA2 olarak bilinen iki farkl\u0131 gen, normalde kanserin \u00f6nlenmesine yard\u0131mc\u0131 olan DNA tamirinde g\u00f6revlidir.<\/p>\n

\"GenoXhere

GenoXhere BRCA<\/p><\/div>\n

Ancak, baz\u0131 insanlarda bu genlerde do\u011fal bir mutasyon meydana gelir ve bu ki\u015filer meme kanseri, yumurtal\u0131k kanseri ve di\u011fer kanser t\u00fcrlerine yakalanma riski ta\u015f\u0131rlar. Bu ki\u015filer, BRCA mutasyonlar\u0131ndan kaynaklanan kanser riskini azaltmak i\u00e7in \u00e7e\u015fitli \u00f6nleyici tedbirler alabilirler. BRCA mutasyonlar\u0131n\u0131n ke\u015ffi, ailelerde genetik ge\u00e7i\u015fli meme kanseri ve yumurtal\u0131k kanseri riskini belirlemeye yard\u0131mc\u0131 olabilir ve risk alt\u0131ndaki bireylerin erken te\u015fhis ve \u00f6nleyici tedbirler almas\u0131n\u0131 sa\u011flayabilir.<\/p>\n\n\n\n\n\n\n\n\n
Gen :<\/strong><\/td>\nBRCA1 | BRCA2<\/td>\n<\/tr>\n
Y\u00f6ntem :<\/strong><\/td>\nT\u00fcm Gen Dizi Analizi<\/td>\n<\/tr>\n
Raporlama S\u00fcresi :<\/strong><\/td>\n8 Hafta (+\/- 2 Hafta)<\/td>\n<\/tr>\n
Prenatal\/ Postnatal:<\/strong><\/strong><\/td>\nPostnatal<\/td>\n<\/tr>\n
Gerekli Numune<\/strong>:<\/td>\nEDTA’l\u0131 Kan (2-4 ml)<\/td>\n<\/tr>\n
Saklama \/ Ta\u015f\u0131ma S\u0131cakl\u0131\u011f\u0131:<\/strong><\/td>\n+ 4C\u00b0\/ + 24C\u00b0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

T\u00fcm genetik testlerimiz „Hasta Onam Formu“<\/strong> ve „KVKK Formu“<\/strong>nun imzalanmas\u0131n\u0131n ard\u0131ndan \u00e7al\u0131\u015f\u0131lmaya ba\u015flan\u0131r.<\/p>\n

\n

Detayl\u0131 Bilgi Almak \u0130\u00e7in Bize Mesaj Atabilirsiniz.<\/strong><\/p>\n\n\n\n
[contact-form-7 id=“710″ title=“genetik ba\u015fvuru“]<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Genoks Genetik Hastal\u0131klar De\u011ferlendirme Merkezi T.C. Sa\u011fl\u0131k Bankanl\u0131\u011f\u0131nca denetlenen ve GHDM-SM\/06.15\/01 ruhsat numaras\u0131 ile hizmet veren sa\u011fl\u0131k kurulu\u015fudur. genoks.com.tr web sayfas\u0131nda bulunan bilgiler, genetik de\u011ferlendirme ve\/veya tan\u0131-te\u015fhis ama\u00e7l\u0131 kullan\u0131lmamal\u0131d\u0131r. T\u00fcm i\u00e7erikler bilgilendirme ama\u00e7l\u0131d\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u0160ta je BRCA gen? \u0160ta obuhvata GenoXhere BRCA? BRCA1 i BRCA2 su tumor supresorski geni neophodni za popravku dvolan\u010danih prekida DNK putem homologne rekombinacije. Patogene germinativne varijante u bilo kojem od njih zna\u010dajno pove\u0107avaju do\u017eivotni rizik od raka dojke (~55-72% [\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"doc_category":[208],"doc_tag":[92,105,106],"class_list":["post-3291","docs","type-docs","status-publish","hentry","doc_category-genoks-gdhm-genetic-tests-sr","doc_tag-brca","doc_tag-kalitsal","doc_tag-kanser"],"aioseo_notices":[],"year_month":"2026-05","word_count":410,"total_views":0,"reactions":{"happy":0,"normal":0,"sad":0},"author_info":{"name":"admin","author_nicename":"admin","author_url":"https:\/\/genoks.com.tr\/sr\/author\/admin\/"},"doc_category_info":[{"term_name":"\u0413\u0435\u043d\u0435\u0442\u0441\u043a\u0438 \u0442\u0435\u0441\u0442\u043e\u0432\u0438 Genoks GDHM","term_url":"https:\/\/genoks.com.tr\/sr\/docs-category\/genoks-gdhm-genetic-tests-sr\/"}],"doc_tag_info":[{"term_name":"BRCA","term_url":"https:\/\/genoks.com.tr\/docs-tag\/brca\/"},{"term_name":"Kal\u0131tsal","term_url":"https:\/\/genoks.com.tr\/docs-tag\/kalitsal\/"},{"term_name":"kanser","term_url":"https:\/\/genoks.com.tr\/docs-tag\/kanser\/"}],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t